BDBM200990 1-[4-(3,5-dimethyl-6-oxo-1,6- dihydropyridazin-4-yl)-3-methylphenoxy] isoquinoline-8-carbonitrile::US9540352, example 14

SMILES Cc1cc(Oc2nccc3cccc(C#N)c23)ccc1-c1c(C)n[nH]c(=O)c1C

InChI Key InChIKey=UVNSFRYXGBVTBR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200990   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM200990(US9540352, example 14 | 1-[4-(3,5-dimethyl-6-oxo-1...)
Affinity DataKi:  261nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2018
Entry Details
Go to US Patent