BDBM200823 2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)-pyridin-3-yl]-2-aza-spiro[4.5]decan-1-one::US9533995, 6

SMILES C[C@H]1CCCN1[C@@H]1CCN(C1)c1ccc(N2CCC3(CCCCC3)C2=O)c(C)n1

InChI Key InChIKey=KJGSQLZEBZOCDD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200823   

TargetHistamine receptor H3(Rhesus macaque)
Sanofi

US Patent
LigandPNGBDBM200823(2-[2-methyl-6-((2s,3'r)-2-methyl-[1,3']bip...)
Affinity DataKi:  56.5nMAssay Description:Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent