BDBM200755 US9233108, 20::US9757383, Example 20

SMILES CC(Cc1ccc(OCC(=O)NCCN[C@H]2CC[C@@H](CC2)OC(=O)C(O)(c2cccs2)c2cccs2)cc1)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12

InChI Key InChIKey=KLPDYSZBSHOUAD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 200755   

TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM200755(US9233108, 20 | US9757383, Example 20)
Affinity DataIC50: 3.10nMT: 2°CAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM200755(US9233108, 20 | US9757383, Example 20)
Affinity DataIC50: 3.60nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM200755(US9233108, 20 | US9757383, Example 20)
Affinity DataIC50: 3.10nMAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM200755(US9233108, 20 | US9757383, Example 20)
Affinity DataIC50: 3.60nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent