BDBM200752 US9233108, 17::US9757383, Example 16

SMILES CN(CCCn1nnc2cc(CNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)ccc12)[C@H]1CC[C@@H](CC1)OC(=O)[C@@](O)(C1CCCC1)c1cccs1

InChI Key InChIKey=UWSDYYMSDATFRY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 200752   

TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM200752(US9233108, 17 | US9757383, Example 16)
Affinity DataIC50: 13nMT: 2°CAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM200752(US9233108, 17 | US9757383, Example 16)
Affinity DataIC50: 0.600nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

TargetBeta-2 adrenergic receptor(Human)
Almirall

US Patent
LigandPNGBDBM200752(US9233108, 17 | US9757383, Example 16)
Affinity DataIC50: 12nMAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Almirall

US Patent
LigandPNGBDBM200752(US9233108, 17 | US9757383, Example 16)
Affinity DataIC50: 5.90nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent