BDBM200561 US9227973, 5 isomer A::US9227973, 6 isomer A

SMILES O=C(NC1CC(Cc2cccnc12)c1ccccc1)c1cnc2C[C@]3(Cc2c1)C(=O)Nc1ncccc31

InChI Key InChIKey=AWNPJVVXALCZPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 200561   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200561(US9227973, 6 isomer A | US9227973, 5 isomer A)
Affinity DataIC50: 22nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200561(US9227973, 6 isomer A | US9227973, 5 isomer A)
Affinity DataIC50: 78nMT: 2°CAssay Description:RECOMBINANT RECEPTOR FUNCTIONAL ASSAY (Assay B): Cells were resuspended in DMEM/F12 (Hyclone) supplemented with 1 g/L BSA and 300 uM isobutyl-methylx...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent