BDBM200324 US9227956, 9

SMILES Cc1cnc2n(nnc2c1)-c1ccc(nc1)C(=O)N([C@@H]1CCCNC1)c1ncccc1Cl

InChI Key InChIKey=UVVXRMZCPKQLAO-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 200324   

LigandPNGBDBM200324(US9227956, 9)
Affinity DataIC50: 1.80E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
Go to US Patent

LigandPNGBDBM200324(US9227956, 9)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human ERG by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details Article
PubMed
LigandPNGBDBM200324(US9227956, 9)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of full length human PCSK9 expressed in human Huh-7 cells by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM200324(US9227956, 9)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of dofetilide binding to human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details Article
PubMed