BDBM200320 US9227956, 5

SMILES Clc1cccnc1N([C@@H]1CCCNC1)C(=O)c1ccc(cn1)-n1nnc2cccnc12

InChI Key InChIKey=OZBMIGDQBBMIRA-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 200320   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Pfizer

US Patent

LigandBDBM200320(US9227956, 5)Copy SMILESCopy InChI

Affinity DataIC50: 1.50E+3nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/14/2016
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM200320(US9227956, 5)Copy SMILESCopy InChI

Affinity DataKi:  2.88E+4nMAssay Description:Inhibition of dofetilide binding to human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/18/2020
Entry Details Article
Copy Entry DOIPubMed
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