BDBM200300 5-[4-amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine::cid_122163152

SMILES CCOC(Cn1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12)OCC

InChI Key InChIKey=PSICWGWNIOOULV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 200300   

TargetSerine/threonine-protein kinase mTOR(Human)
Innovative Therapeutics Lab

Curated by PubChem BioAssay
LigandPNGBDBM200300(5-[4-amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyr...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2016
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase mTOR(Human)
Innovative Therapeutics Lab

Curated by PubChem BioAssay
LigandPNGBDBM200300(5-[4-amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandPNGBDBM200300(5-[4-amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyr...)
Affinity DataIC50: 981nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Innovative Therapeutics Lab

Curated by PubChem BioAssay
LigandPNGBDBM200300(5-[4-amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed