BDBM20026 3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]-N-benzylaniline::Quinoline 38

SMILES FC(F)(F)c1cccc2c(-c3cccc(NCc4ccccc4)c3)c(cnc12)C(=O)c1ccccc1

InChI Key InChIKey=CUPCXDRVHZGUGE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20026   

TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM20026(3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]-N-b...)
Affinity DataIC50: 241nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM20026(3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]-N-b...)
Affinity DataIC50: 45nM EC50:  770nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2008
Entry Details Article
PubMed