BDBM19994 3-benzoyl-4-phenyl-8-(trifluoromethyl)quinoline::Quinoline 4::phenyl-[4-phenyl-8-(trifluoromethyl)quinolin-3-yl]methanone

SMILES FC(F)(F)c1cccc2c(-c3ccccc3)c(cnc12)C(=O)c1ccccc1

InChI Key InChIKey=VLCMRTMCMQJSKM-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19994   

TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM19994(3-benzoyl-4-phenyl-8-(trifluoromethyl)quinoline | ...)
Affinity DataIC50: 260nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM19994(3-benzoyl-4-phenyl-8-(trifluoromethyl)quinoline | ...)
Affinity DataIC50: 107nM EC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed