BDBM199228 US9216998, 26

SMILES FC(F)(F)c1c(CCCc2ccccc2)n2CCOc3cccc1c23

InChI Key InChIKey=VPLAFDBAMQZJCW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199228   

TargetEndothelial lipase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199228(US9216998, 26)
Affinity DataIC50: 413nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199228(US9216998, 26)
Affinity DataIC50: 618nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent