BDBM199223 US9216998, 6

SMILES Oc1cc2CCCn3c(CCc4ccccc4)c(c(c1)c23)C(F)(F)F

InChI Key InChIKey=DMFJQYGSFVOAGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199223   

TargetEndothelial lipase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199223(US9216998, 6)
Affinity DataIC50: 71nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199223(US9216998, 6)
Affinity DataIC50: 136nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent