BDBM199219 US9216998, 7::US9216998, Reference Compound 2

SMILES FC(F)(F)c1c(CCc2ccccc2)n2CCCc3cccc1c23

InChI Key InChIKey=FYGQTNWKBNYVQB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 199219   

TargetEndothelial lipase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 17nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 22nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 26nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM199219(US9216998, 7 | US9216998, Reference Compound 2)
Affinity DataIC50: 48nMpH: 7.2Assay Description:To assay for cell surface lipase activity, cells expressing human endothelial lipase (EL) or LPL were plated in CellBIND 384-well plates (Corning, Lo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent