BDBM19919 3-arylquinazolinone, 1aak::3-arylquinazolinone, 1af::7-hydroxy-3-(4-hydroxyphenyl)-5-methoxy-3,4-dihydroquinazolin-4-one

SMILES COc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12

InChI Key InChIKey=VHZMSDGAAMARIU-UHFFFAOYSA-N

Data  2 EC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19919   

TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19919(3-arylquinazolinone, 1aak | 7-hydroxy-3-(4-hydroxy...)
Affinity DatapH: 8.0 T: 2°CAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM19919(3-arylquinazolinone, 1aak | 7-hydroxy-3-(4-hydroxy...)
Affinity DataAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19919(3-arylquinazolinone, 1aak | 7-hydroxy-3-(4-hydroxy...)
Affinity DataEC50:  8.51E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Bristol-Myers Squibb

LigandPNGBDBM19919(3-arylquinazolinone, 1aak | 7-hydroxy-3-(4-hydroxy...)
Affinity DataEC50:  8.51E+3nMAssay Description:Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMed