BDBM199121 N-(4-(1-(4,6-bis((3-aminopropyl)amino)-1,3,5-triazin-2-yl)-5-(4-methoxyphenyl)-1H-pyrazol-3-yl)phenyl)-4-methylbenzenesulphonamide (8c)

SMILES COc1ccc(cc1)-c1cc(nn1-c1nc(NCCCN)nc(NCCCN)n1)-c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

InChI Key InChIKey=ZBKIKGKYISSOFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 199121   

Target72 kDa type IV collagenase(Rat)
Zhejiang Hospital

LigandPNGBDBM199121(N-(4-(1-(4,6-bis((3-aminopropyl)amino)-1,3,5-triaz...)
Affinity DataIC50: 189nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Rat)
Zhejiang Hospital

LigandPNGBDBM199121(N-(4-(1-(4,6-bis((3-aminopropyl)amino)-1,3,5-triaz...)
Affinity DataIC50: 156nMpH: 7.5 T: 2°CAssay Description:For this assay, the reagents used as follows. The substrate corresponds to Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg 25 mm in assay buffer. This low-fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details Article
PubMed