BDBM199092 (1r,5s,7s)-3-oxa-9-azabicyclo[3.3.1]nonan- 7-yl 1-(pyridin-4-yl)-1h-indole-3-carboxylate, 2,2,2-trifluoroacetate::US10125145, Cpd. No. 6::US9670229, 2::US9670229, 6

SMILES CN1C2COCC1CC(C2)NC(=O)c1cn(-c2cccnc2)c2ccccc12

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 199092   

Target5-hydroxytryptamine receptor 3A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM199092(US9670229, 6 | (1r,5s,7s)-3-oxa-9-azabicyclo[3.3.1...)
Affinity DataIC50: 0.510nMT: 2°CAssay Description:The 5-HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM199092(US9670229, 6 | (1r,5s,7s)-3-oxa-9-azabicyclo[3.3.1...)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:The 5-HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM199092(US9670229, 6 | (1r,5s,7s)-3-oxa-9-azabicyclo[3.3.1...)
Affinity DataIC50: 0.510nMAssay Description:The 5-HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 3A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM199092(US9670229, 6 | (1r,5s,7s)-3-oxa-9-azabicyclo[3.3.1...)
Affinity DataIC50: 1.10nMAssay Description:The 5-HT3 antagonist activity of the compounds of the invention was determined by measuring the ability of the compounds to inhibit the calcium flux ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
Go to US Patent