BDBM198875 US9221797, 48

SMILES OC(=O)C=Cc1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCCCC1

InChI Key InChIKey=WEVPNKITDWKLNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198875   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM198875(US9221797, 48)
Affinity DataIC50: 3.90nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM198875(US9221797, 48)
Affinity DataIC50: 5.30nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent