BDBM198873 US9221797, 45

SMILES CC1CCCC(=C1C)c1cc(ccc1NC(=O)c1ncc([nH]1)C#N)C(C)(C)N1CCCC1

InChI Key InChIKey=FBGWQVAKZUGXQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198873   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM198873(US9221797, 45)
Affinity DataIC50: 0.600nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent