BDBM198805 BDBM198821::US9221796, 95, P-2

SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)[C@@H]1CCN(Cc2ccc(Cl)cc2)C1=O

InChI Key InChIKey=OIMXBHXLIVXEEQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 198805   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198805(BDBM198821 | US9221796, 95, P-2)
Affinity DataKi:  4.60nM ΔG°:  -12.3kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198805(BDBM198821 | US9221796, 95, P-2)
Affinity DataKi:  12nM ΔG°:  -11.7kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent