BDBM198796 US9221796, 88

SMILES Oc1ccc(cc1)[C@H]1CCN(C[C@@H]1F)[C@@H]1CCN(Cc2ccc(cc2)C(F)(F)F)C1=O

InChI Key InChIKey=YALQZTSLSZMJHO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 198796   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198796(US9221796, 88)
Affinity DataKi:  5.30nM ΔG°:  -12.2kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent