BDBM198743 BDBM198744::BDBM198745::BDBM198746::US9221796, 51, P-1

SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1

InChI Key InChIKey=HKJQOALDDUBRBV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 198743   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198743(BDBM198745 | BDBM198744 | BDBM198746 | US9221796, ...)
Affinity DataKi:  7.60nM ΔG°:  -12.0kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198743(BDBM198745 | BDBM198744 | BDBM198746 | US9221796, ...)
Affinity DataKi:  11nM ΔG°:  -11.8kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198743(BDBM198745 | BDBM198744 | BDBM198746 | US9221796, ...)
Affinity DataKi:  30nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198743(BDBM198745 | BDBM198744 | BDBM198746 | US9221796, ...)
Affinity DataKi:  660nM ΔG°:  -9.13kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent