BDBM198672 BDBM198673::BDBM198674::BDBM198675::BDBM198676::BDBM198719::BDBM198720::US9221796, 8

SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O

InChI Key InChIKey=NIPVYFDEJFFCLH-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 198672   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198672(BDBM198675 | BDBM198674 | BDBM198676 | BDBM198720 ...)
Affinity DataKi:  5.70nM ΔG°:  -12.2kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198672(BDBM198675 | BDBM198674 | BDBM198676 | BDBM198720 ...)
Affinity DataKi:  160nM ΔG°:  -10.0kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198672(BDBM198675 | BDBM198674 | BDBM198676 | BDBM198720 ...)
Affinity DataKi:  180nM ΔG°:  -9.97kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198672(BDBM198675 | BDBM198674 | BDBM198676 | BDBM198720 ...)
Affinity DataKi:  420nM ΔG°:  -9.42kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198672(BDBM198675 | BDBM198674 | BDBM198676 | BDBM198720 ...)
Affinity DataKi:  650nM ΔG°:  -9.14kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198672(BDBM198675 | BDBM198674 | BDBM198676 | BDBM198720 ...)
Affinity DataKi:  1.40E+3nM ΔG°:  -8.65kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM198672(BDBM198675 | BDBM198674 | BDBM198676 | BDBM198720 ...)
Affinity DataKi:  5.00E+3nM ΔG°:  -7.83kcal/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent