BDBM19846 (1R,2R)-N-(cyanomethyl)-2-{2-[4-(methylsulfanyl)phenyl]phenyl}cyclohexane-1-carboxamide::Cyclohexanecarboxamide derivative, 24a::racemic mixture

SMILES CSc1ccc(cc1)-c1ccccc1[C@@H]1CCCC[C@H]1C(=O)NCC#N

InChI Key InChIKey=UKQULZSZDDFLST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19846   

TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19846((1R,2R)-N-(cyanomethyl)-2-{2-[4-(methylsulfanyl)ph...)
Affinity DataIC50: 2.60nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed