BDBM197762 US9216986, 7-Chloro-2-[2-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-quinoline::US9801878, 7-Chloro-2-[2-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-quinoline

SMILES Cc1ncc(C)n2nc(CCc3ccc4ccc(Cl)cc4n3)nc12

InChI Key InChIKey=FATJBQNFQIWTPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197762   

LigandPNGBDBM197762(US9216986, 7-Chloro-2-[2-(5,8-dimethyl-[1,2,4]tria...)
Affinity DataIC50: 52nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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LigandPNGBDBM197762(US9216986, 7-Chloro-2-[2-(5,8-dimethyl-[1,2,4]tria...)
Affinity DataIC50: 39nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent