BDBM197756 US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-7-fluoro-quinolin-4-ol::US9801878, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-7-fluoro-quinolin-4-ol

SMILES Cc1cnc(C)c2nc(CCc3cc(O)c4ccc(F)cc4n3)nn12

InChI Key InChIKey=GCGYJTLJUUHVRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197756   

LigandPNGBDBM197756(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 500nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

LigandPNGBDBM197756(US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50: 300nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent