BDBM197751 BDBM197752::US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-6-fluoro-quinoline::US9801878, 2-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-ethyl]-6-fluoro-quinoline

SMILES Cc1ncc(C)n2nc(CCc3ccc4cc(F)ccc4n3)nc12

InChI Key InChIKey=AOLYXBUFENUNSR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 197751   

LigandPNGBDBM197751(BDBM197752 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 24nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

LigandPNGBDBM197751(BDBM197752 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 26nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

LigandPNGBDBM197751(BDBM197752 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 120nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent

LigandPNGBDBM197751(BDBM197752 | US9216986, 2-[2-(5,8-Dimethyl-[1,2,4]...)
Affinity DataIC50: 52nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent