BDBM197748 US9216986, 4-Chloro-8-fluoro-2-[(E)-2-(8-methoxy-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-vinyl]-quinoline::US9801878, 4-Chloro-8-fluoro-2-[(E)-2-(8-methoxy-5-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-vinyl]-quinoline

SMILES COc1ccc(C)n2nc(\C=C\c3cc(Cl)c4cccc(F)c4n3)nc12

InChI Key InChIKey=IGJRVXPXQLTRFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197748   

LigandPNGBDBM197748(US9216986, 4-Chloro-8-fluoro-2-[(E)-2-(8-methoxy-5...)
Affinity DataIC50: 270nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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LigandPNGBDBM197748(US9216986, 4-Chloro-8-fluoro-2-[(E)-2-(8-methoxy-5...)
Affinity DataIC50: 24nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
Go to US Patent