BDBM197704 US9216981, 33

SMILES Fc1ccc(NS(=O)(=O)c2cccc(Cl)c2)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=TUORYODHIROMIM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197704   

TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandPNGBDBM197704(US9216981, 33)
Affinity DataIC50: 80nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
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TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandPNGBDBM197704(US9216981, 33)
Affinity DataEC50:  770nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent