BDBM197687 US9216981, 15

SMILES Fc1ccc(NS(=O)(=O)c2ccco2)c(F)c1Nc1ncccc1-c1ncnc2[nH]cnc12

InChI Key InChIKey=QZRYHOXAGKASKV-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197687   

TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandPNGBDBM197687(US9216981, 15)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:To check the B-Raf kinase inhibitory activity of the compounds of the present invention, the following experiments were conducted.(1) Serial Signalin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase B-raf(Human)
Medpacto

US Patent
LigandPNGBDBM197687(US9216981, 15)
Affinity DataEC50:  1.10E+4nMT: 2°CAssay Description:To check the B-Raf cell activity inhibitory capability of the compounds of the present invention, the following experiments were conducted in A375P c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent