BDBM197631 US9216968, 231::US9732066, 231

SMILES COCc1nc2c(cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1)C(=O)NCC1CCCCCC1

InChI Key InChIKey=ADEGOAPBBTXCBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197631   

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM197631(US9216968, 231 | US9732066, 231)
Affinity DataIC50: 1.90nMAssay Description:mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM197631(US9216968, 231 | US9732066, 231)
Affinity DataIC50: 1.90nMAssay Description:mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent