BDBM197589 US9216968, 189::US9732066, 189

SMILES Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2cc(Cl)ccc2Cl)cc2[nH]c(NCC(C)(C)CO)nc12

InChI Key InChIKey=KXDONWCTYRYOCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197589   

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM197589(US9216968, 189 | US9732066, 189)
Affinity DataIC50: 1.40nMAssay Description:mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
Go to US Patent

TargetProstaglandin E synthase(Human)
Nippon Shinyaku

US Patent
LigandPNGBDBM197589(US9216968, 189 | US9732066, 189)
Affinity DataIC50: 1.40nMAssay Description:mPGES-1 microsome fractions were prepared from CHO-K1 cells transiently transfected with plasmid encoding the human mPGES-1cDNA. Microsomes were dilu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
Go to US Patent