BDBM197158 3-((2-chlorophenyl)thio)-4-hydroxy-6-phenyl-5,6-dihydropyridin-2(1H)-one (4)

SMILES OC1=C(Sc2ccccc2Cl)C(=O)NC(C1)c1ccccc1

InChI Key InChIKey=KHNDKFGFIXWFLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197158   

TargetL-lactate dehydrogenase A chain(Human)
Genentech

LigandPNGBDBM197158(3-((2-chlorophenyl)thio)-4-hydroxy-6-phenyl-5,6-di...)
Affinity DataIC50: 4.00E+3nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

LigandPNGBDBM197158(3-((2-chlorophenyl)thio)-4-hydroxy-6-phenyl-5,6-di...)
Affinity DataIC50: 1.80E+4nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed