BDBM196662 US10202399, Example 22::US9212147, 22

SMILES Cc1ccccc1CCc1cc(O)c(=O)[nH]n1

InChI Key InChIKey=CCXCCRVXWWOUJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 196662   

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196662(US9212147, 22 | US10202399, Example 22)
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196662(US9212147, 22 | US10202399, Example 22)
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details
Go to US Patent

TargetD-amino-acid oxidase(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196662(US9212147, 22 | US10202399, Example 22)
Affinity DataIC50: 3.30nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent