BDBM196563 US9670214, TABLE 16.12

SMILES FC(F)(F)Oc1ccc(Nc2cc(ncn2)-c2ccc(cc2)S(=O)(=O)N2CCCCC2)cc1

InChI Key InChIKey=MBJMKJJABLGJAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196563   

TargetNon-specific protein-tyrosine kinase(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM196563(US9670214, TABLE 16.12)
Affinity DataIC50: 1.06E+3nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetNon-specific protein-tyrosine kinase [T818I](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM196563(US9670214, TABLE 16.12)
Affinity DataIC50: 1.41E+3nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent