BDBM196490 US10202344, Compound 178::US9212139, 178

SMILES CCN(CC)CCn1cc(C(=O)C(N)=O)c2cc(ccc12)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=VRZTWIPACUAKRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196490   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM196490(US9212139, 178 | US10202344, Compound 178)
Affinity DataIC50: 1.03E+3nMpH: 7.3Assay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
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TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM196490(US9212139, 178 | US10202344, Compound 178)
Affinity DataIC50: 1.03E+3nMAssay Description:Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent