BDBM196472 US10202344, Compound 105::US9212139, 105

SMILES OC[C@@H](O)Cc1cn(-c2ccc(Oc3ccc(F)cc3)cc2)c2cc(ccc12)C#N

InChI Key InChIKey=SUAQQAOEEFJZTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196472   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM196472(US9212139, 105 | US10202344, Compound 105)
Affinity DataIC50: 1.65E+3nMpH: 7.3Assay Description:Assay Buffer: The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
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TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM196472(US9212139, 105 | US10202344, Compound 105)
Affinity DataIC50: 1.65E+3nMAssay Description:Recombinant Nav1.7 Cell Line: In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
Go to US Patent