BDBM196374 BDBM196434::US9212130, I-298

SMILES Cc1ccc(Oc2ccc(Nc3ncc(NC(=O)C(CO)CO)c(=O)n3Cc3ccc(Cl)cc3)cc2)cn1

InChI Key InChIKey=UDXYDKVTYNXTLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196374   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM196374(BDBM196434 | US9212130, I-298)
Affinity DataIC50: 8nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM196374(BDBM196434 | US9212130, I-298)
Affinity DataIC50: 7nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details
Go to US Patent