BDBM19486 2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde::Aldehyde Inhibitor, 2

SMILES Fc1ccc(c(F)c1F)-c1ccccc1OCC=O

InChI Key InChIKey=SHBOZVYTDQJORM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19486   

TargetCathepsin S(Human)
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi:  490nM ΔG°:  -8.95kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin K(Human)
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi:  1.51E+3nM ΔG°:  -8.25kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi:  1.54E+3nM ΔG°:  -8.24kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of California Berkeley

LigandPNGBDBM19486(2-[2-(2,3,4-trifluorophenyl)phenoxy]acetaldehyde |...)
Affinity DataKi: >1.50E+4nM ΔG°: >-6.84kcal/molepH: 6.1 T: 2°CAssay Description:The proteolytic cleavage of N-acyl aminocoumarins by cathepsins was conducted in Dynatech Microfluor fluorescence 96-well microtiter plates, and read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2007
Entry Details Article
PubMed