BDBM19447 2-(4-methanesulfonylphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1-benzothiophen-6-ol::Arzoxifene analogue, 13::CHEMBL389907

SMILES CS(=O)(=O)c1ccc(cc1)-c1sc2cc(O)ccc2c1Oc1ccc(OCCN2CCCCC2)cc1

InChI Key InChIKey=KUWSWTJKKAYVBV-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 19447   

TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19447(CHEMBL389907 | 2-(4-methanesulfonylphenyl)-3-{4-[2...)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19447(CHEMBL389907 | 2-(4-methanesulfonylphenyl)-3-{4-[2...)
Affinity DataIC50: 1.80E+3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19447(CHEMBL389907 | 2-(4-methanesulfonylphenyl)-3-{4-[2...)
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]estradiol from human recombinant ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19447(CHEMBL389907 | 2-(4-methanesulfonylphenyl)-3-{4-[2...)
Affinity DataKi:  13.6nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed