BDBM19446 2-phenyl-3-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1-benzothiophen-6-ol::Arzoxifene analogue, 12

SMILES Oc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(sc2c1)-c1ccccc1

InChI Key InChIKey=AMGFCHULXKRDJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 19446   

TargetEstrogen receptor(Human)
University of Illinois At Chicago

LigandPNGBDBM19446(2-phenyl-3-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1...)
Affinity DataIC50: 10.9nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois At Chicago

LigandPNGBDBM19446(2-phenyl-3-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1...)
Affinity DataIC50: 16.3nMpH: 7.5 T: 2°CAssay Description:Arzoxifene and its analogues were assayed in the standard ER competitive radioligand binding assay, using full length human recombinant ER-alpha and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed