BDBM193886 3(R)-4-(4-chlorobenzyl)-6-(3,5-dimethylisoxazol-4-yl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (5c)::4(R)-4-cyclopentyl-6-(3,5-dimethylisoxazol-4-yl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (5d)

SMILES C[C@H]1N(Cc2ccc(Cl)cc2)c2cc(ccc2NC1=O)-c1c(C)noc1C

InChI Key InChIKey=NNGSYKPKUIVPQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193886   

TargetBromodomain-containing protein 4 [44-168](Human)
China Pharmaceutical University

LigandPNGBDBM193886(4(R)-4-cyclopentyl-6-(3,5-dimethylisoxazol-4-yl)-3...)
Affinity DataIC50: 440nMT: 2°CAssay Description:11 compounds were evaluated against BRD4-BD1 in vitro with compound 28a as the reference compound. BRD4 (44-168 aa) was bought from Active Motif. Aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2016
Entry Details Article
PubMed