BDBM19388 2,4-diaminopyrimidine derivative, 8d::6-[(benzyloxy)methyl]-5-[4-({[4-(trifluoromethane)sulfonylphenyl]methyl}amino)phenyl]pyrimidine-2,4-diamine

SMILES Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1

InChI Key InChIKey=YIRVMBRTDCZPQZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19388   

TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19388(6-[(benzyloxy)methyl]-5-[4-({[4-(trifluoromethane)...)
Affinity DataIC50: 1nM EC50:  85nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed