BDBM193820 US9670209, Compound 322 1-((R)-3-((1R,3R,5S)-3-(prop-2-ynyloxy)-8-azabicyclo[3.2.1]octan-8-yl)-2-methylpropyl)-6-methoxy-1H-indazole

SMILES COc1ccc2cnn(C[C@H](C)CN3[C@H]4CC[C@@H]3C[C@@H](C4)OCC#C)c2c1

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193820   

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193820(US9670209, Compound 322 1-((R)-3-((1R,3R,5S)-3-(pr...)
Affinity DataEC50:  10nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193820(US9670209, Compound 322 1-((R)-3-((1R,3R,5S)-3-(pr...)
Affinity DataEC50:  79nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent