BDBM19382 2,4-diaminopyrimidine derivative, 7h::6-ethyl-5-[4-({[4-(trifluoromethane)sulfonylphenyl]methyl}amino)phenyl]pyrimidine-2,4-diamine

SMILES CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(cc2)S(=O)(=O)C(F)(F)F)cc1

InChI Key InChIKey=GNKWFVBWMRYDNB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19382   

TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19382(6-ethyl-5-[4-({[4-(trifluoromethane)sulfonylphenyl...)
Affinity DataIC50: 21nM EC50:  690nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed