BDBM193806 US9670209, Compound 316 1-((R)-3-(3-(cyclopropylmethoxy)-8-aza-bicyclo[3.2.1]octan-8-yl)-2-methylpropyl)-3-methyl-1H-indazole

SMILES C[C@H](CN1[C@H]2CC[C@@H]1C[C@@H](C2)OCC1CC1)Cn1nc(C)c2ccccc12

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 193806   

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193806(US9670209, Compound 316 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193806(US9670209, Compound 316 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  250nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent