BDBM193780 US9670208, Example 467 N-(1-(3-chloro-4-fluorophenyl)-2-(7-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)acetamide

SMILES CC(=O)NC(Cc1nnc2cc(ccn12)-c1ccnc(Nc2ccnn2C)n1)c1ccc(F)c(Cl)c1

InChI Key InChIKey=QYESILPYRFSBFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193780   

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM193780(US9670208, Example 467 N-(1-(3-chloro-4-fluorophen...)
Affinity DataIC50: 1.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
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