BDBM193398 US9670208, Example 131 4-(3-(piperidin-3-yl)-[1,2,4]triazolo[4,3-a]pyridin-7-yl)-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-2-amine

SMILES C1CNCC(C1)c1nnc2cc(ccn12)-c1ccnc(NC2CCOCC2)n1

InChI Key InChIKey=CZGIBSLQLBDQTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193398   

TargetMitogen-activated protein kinase 1 [8-360](Human)
Array Biopharma

US Patent
LigandPNGBDBM193398(US9670208, Example 131 4-(3-(piperidin-3-yl)-[1,2,...)
Affinity DataIC50: 224nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
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