BDBM193163 US9193736, 79

SMILES OC(=O)c1ccc(cc1)-c1c(CCc2ccc3CCCCc3n2)nc2c(ccnn12)N1CCOCC1

InChI Key InChIKey=AIGJUUPJEPLOOT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 193163   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM193163(US9193736, 79)
Affinity DataIC50: 8nMpH: 7.8Assay Description:Rat recombinant PDE10a (rPDE10a) was expressed in Sf9 cells using a recombinant rPDE10a baculovirus construct. Cells were harvested after 48 h of inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2016
Entry Details
Go to US Patent

LigandPNGBDBM193163(US9193736, 79)
Affinity DataIC50: 3nMAssay Description:Human recombinant PDE10A2 was expressed in Sf9 cells, using a recombinant baculovirus construct containing the full length sequence containing a 6 Hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2016
Entry Details
Go to US Patent

LigandPNGBDBM193163(US9193736, 79)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 cells incubated for 60 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed