BDBM193074 US9193726, 62

SMILES Cc1cn(cn1)-c1ccc2C(=O)N(C[C@@H]3CC[C@@H](O3)c3cc(F)c(Cl)c(F)c3)CCn2c1=O

InChI Key InChIKey=WOEGUWOGPNKYRA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 193074   

TargetPresenilin-1(Human)
Pfizer

US Patent
LigandPNGBDBM193074(US9193726, 62)
Affinity DataIC50: 13.3nMT: 2°CAssay Description:The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2016
Entry Details
Go to US Patent