BDBM1930 4-hydroxy-7-methoxy-3-(1-phenylpropyl)-2H-chromen-2-one::Carboxamide-Containing 4-Hydroxycoumarin analogue XI

SMILES CCC(c1ccccc1)C2=C(c3ccc(cc3OC2=O)OC)O

InChI Key InChIKey=CCPGCKQLIHGSCJ-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1930   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM1930(4-hydroxy-7-methoxy-3-(1-phenylpropyl)-2H-chromen-...)
Affinity DataKi:  560nM ΔG°:  -8.44kcal/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM1930(4-hydroxy-7-methoxy-3-(1-phenylpropyl)-2H-chromen-...)
Affinity DataKi:  560nMAssay Description:Binding affinity to HIV-1 protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed